Got it to work !
Create a 3rd query by joining the first two, include all the data items from both, don't put anything in the measures and add both the meausres to the rows, then create the calculation (Diff) between both the measures.
However, with this scenario, if I do a Total of the first or second query, it doesn't work. Wonder why? Not a big deal, because I have the totals in the form of summary in the 3rd query!
That being said, if anybody has a better solution, it is welcome !